Indivina

Indivina is a combined HRT tablet containing two synthetic hormones: medroxyprogesterone acetate and estradiol valerate. These hormones work together to manage your menopausal symptoms. Indivina is a good choice for women who are postmenopausal.

Indivina can also be used as a second option for treating osteoporosis. Postmenopausal women who have a higher risk of developing brittle bones may find it beneficial as well.

As it's available in a low-dose combined tablet, it can be a good choice for women who are more sensitive to the side effects of oestrogen and progesterone.

During the menopause, your ovaries produce less oestrogen. This drop in oestrogen can lead to symptoms like hot flushes, vaginal dryness, discomfort during sex, low mood or anxiety, difficulty sleeping, reduced sex drive, and night sweats.

These symptoms can be uncomfortable for some women, and the synthetic oestrogen in Indivina, called estradiol valerate, helps to relieve them by compensating for the decrease in the body's natural oestrogen.

On its own, while it helps manage menopause symptoms, synthetic oestrogen can cause the womb to continue growing. If this isn't monitored, it could lead to womb cancer (if you still have your womb). This is where progestin (medroxyprogesterone acetate) is important; it balances the effects of oestrogen on the womb lining and lowers your risk of cancer.

The oestrogen in Indivina can help prevent osteoporosis. During menopause, a drop in this hormone can lead to thinner bones, making them more likely to break. HRT treatments like Indivina can effectively replace the natural oestrogen your body is losing.

If you've gone through menopause (meaning you haven't had a period for a year) and haven't had a hysterectomy, continuous combined HRT options such as Indivina are typically recommended. If this doesn't match your situation regarding menopause, a different type of HRT might be more suitable for you.

For instance, if you're experiencing menopausal symptoms but still having your periods, sequential (or cyclical) HRT products such as Elleste Duet are often recommended. On the other hand, if you've had your womb removed during a hysterectomy, oestrogen-only HRT products like Elleste Solo and Estradot patches are generally considered better treatment options.

Indivina is a type of combined HRT available as tablets. Many women appreciate the convenience of tablets since they're easy to take. However, if you prefer using a skin patch, the Evorel Conti patch offers a direct topical alternative to Indivina.

Various HRT treatments have different hormone levels, helping you find the right balance between effective treatment and what suits you best.

There is some evidence that using combined HRT products like Indivina for a long time might slightly increase your risk of breast cancer by 1%.

To give you an idea of the increased risk: out of every 1,000 women aged from menopause to 69 who aren't on continuous combined HRT, 13 might develop breast cancer. If 1,000 women in this age group use continuous combined HRT for five years or more, an extra 10 women might develop breast cancer.

It's known that there's a small increase in the risk of ovarian cancer for women using HRT, but it's quite minor. Out of every 1,000 women who use HRT for five years, there might be one extra case of ovarian cancer.

HRT tablets, such as Indivina, are associated with a slightly increased risk of blood clots, unlike patches or gels. Studies indicate that using HRT tablets could result in nine additional cases of venous thromboembolism per 10,000 women annually.

What's best for you depends on how your body reacts to the treatment. Typically, you'll begin with the lowest dose, which is 1mg of estradiol and 2.5mg of medroxyprogesterone, to see how well it manages your condition. If your symptoms haven't improved after three months on this dose, you should talk to our clinician, who may recommend increasing it.

If you feel that the Indivina 1mg/5mg or 2mg/5mg doses are too strong, our clinician can adjust them to a level that's more comfortable for you.

It really depends on how sensitive you are to the hormones progestogen and oestrogen found in these treatments. Premique, similar to Indivina, is a continuous combined HRT available in a low dose. If you tend to experience side effects from progestogen and oestrogen, these might be suitable options for you.

Both treatments have the same type of progesterone, called medroxyprogesterone acetate, but Premique contains less of it than Indivina. Therefore, if you're prone to side effects from this progestogen, Premique might be the better choice for you.

Premique includes conjugated oestrogen, which is a blend of various oestrogens, while Indivina contains an oestrogen known as estradiol. This could help determine which treatment is more suitable for you.

With a Treated subscription, you can change whenever you like.

Simply log into your account and send a message to our clinician. They'll consider any side effects or symptoms you're having and can suggest different HRT treatments that might be more suitable for you.

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