SKU: 1667791565

Osphos® 51mg/ml solution for Injection 15ml

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Description

Osphos® 51mg/ml solution for Injection 15mlClodronate Injection for Bone Health Mobility For Horses This product is intended to relieve clinical forelimb lameness caused by bone resorption processes in the distal sesamoid (navicular bone) in adult horses. Active ingredient: Clodronic acid Pack sizes: 51mg ml solution for injection, available in a 15ml glass vial. Indications for use: Osphos is a bisphosphonate administered via injection, designed to manage clinical symptoms related to

Clodronate Injection for Bone Health / Mobility

For Horses

This product is intended to relieve clinical forelimb lameness caused by bone resorption processes in the distal sesamoid (navicular bone) in adult horses.

Active ingredient: Clodronic acid

Pack sizes: 51mg/ml solution for injection, available in a 15ml glass vial.

Indications for use: Osphos® is a bisphosphonate administered via injection, designed to manage clinical symptoms related to navicular syndrome in horses aged 4 years and older. Osphos® is the only bisphosphonate that the FDA has approved for intramuscular administration in horses. The active component, Clodronate, is known from laboratory and in vitro studies to prevent bone resorption by decreasing the number of active osteoclasts, irrespective of the factors causing osteoclast activity, and it also inhibits the formation and breakdown of calcium phosphate crystals within the bone matrix.

Dosage: Administer 1.8mg/kg via intramuscular injection (IM), not exceeding a total dose of 900mg per horse. Distribute the total volume evenly among three different injection sites.

Storage: Store below 25°C in a cool, dry environment. Discard any remaining solution in the vial, as Osphos® does not contain preservatives.


Expires on 31 Jul 2027
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SKU: 1667791565

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4.1 ★★★★★
Based on 13 reviews
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A
Verified Purchase
Amazon Customer
Birmingham, US
★★★★★ 5
Dogs love them
3 dogs all fight over these bones
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 1, 2023
S
Verified Purchase
Shelli Williamson
Houston, US
★★★★★ 2
After 2 weeks update 9 month review
Updated. 9 months of aggressive chewing. Pic 2 - Purchased this 2 weeks ago. I have two Pitties. An 8 yr old 80lbs and a 2 yr old 45 lbs. Little pieces flake off as they chew. It is hard finding tough toys for very aggressive chewers. I’m not impressed by these. However, the dogs do love them.
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Reviewed in the United States on July 29, 2023
A
Verified Purchase
artistgirl
Battle Creek, US
★★★★★ 5
Dog love them
Great dog are kept busy
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Reviewed in the United States on June 18, 2023
T
Verified Purchase
Timothy G
Pawtucket, US
★★★★★ 5
Chew incessant dogs
Color: 1PC-Beef-Red
Very tough, My Dashound is a Tasmanian Devil & young this has really slowed his roll, and still enjoying the chewing & licking with peanut butter. Great item!
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Reviewed in the United States on June 1, 2026
M
Verified Purchase
Matthew Nichter
Massapequa, US
★★★★★ 5
Durable!
Color: 1PC-Beef-Red
Alright, here's a product review for those Tough Dog Toys: Finally, a Toy That Survives My Monster! - Tough Dog Toys Review As the owner of a determined (and I mean determined) large breed chewer, finding toys that last longer than five minutes has been a constant and often frustrating quest. I've gone through countless plush toys ripped to shreds, rubber toys with chunks missing, and even some "indestructible" toys that met their demise far too quickly. That's why I was both hopeful and skeptical when I came across the Tough Dog Toys, designed specifically for aggressive chewers and large breeds. Let me tell you, these bone-shaped nylon toys are living up to their name. My power-chewing Labrador has been going at this thing for days now, and I'm genuinely impressed. Where other toys have succumbed to his relentless gnawing, the Tough Dog Toy has held its own. There are some minor teeth marks, as expected, but absolutely no significant damage, no pieces torn off, and no signs of imminent destruction. "Almost indestructible" might actually be an understatement! The design is simple but effective. The solid nylon construction feels incredibly durable, and the bone shape is easy for my dog to grip and maneuver. It's also a good size for a large breed – substantial enough that he can really get a good chew going without it disappearing in his mouth. What I appreciate most is the peace of mind this toy provides. I no longer have to constantly supervise playtime, fearing that he'll ingest pieces of a destroyed toy. This feels like a safe and long-lasting option for even the most enthusiastic chewers. Pros: * Truly durable – stands up to aggressive chewing from a large breed. * Solid nylon construction feels virtually indestructible. * Safe design with no small parts to break off. * Good size and shape for large dogs to grip and enjoy. * Provides long-lasting entertainment. Cons: * May show some teeth marks over time (though this hasn't compromised its integrity). * It's a fairly hard material, so dogs who prefer softer toys might not be as interested. Overall: If you're at your wit's end trying to find a toy that can withstand your aggressive chewing large breed dog, I highly recommend giving the Tough Dog Toys a try. This bone toy has proven to be the most durable option we've encountered, offering excellent value for money and, most importantly, a safe and engaging chewing experience for your furry friend. Five out of five paws!
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Reviewed in the United States on April 23, 2025

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